Kitchen & Sink Repair

Despite the consensus among researchers on the potential of CBD as a neuroprotective agent, larger and well-designed randomized clinical trials will be necessary...

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin.Pharmacokinetics, Safety, and Tolerability...

Studies show that CBD can increase AEA concentration by blocking the AEA membrane transporter (AMT) or the FAAH enzyme, which catalyzes AEA hydrolysis.Cannabidiol: A...

A systematic review.Nonpsychotropic Plant Cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), Activate and Desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) Channels in Vitro: Potential for the...

Therefore, double-blind, placebo-controlled, randomized trials with larger samples of patients with PD are needed to elucidate the...

An open-label pilot study conducted in PD patients showed that oral doses of CBD ranging from 150-400 mg/day, combined with...

At low concentrations (sub-micromolar scale), CBD binds to equilibrative nucleoside transporter (ENT), transient receptor potential melastatin type 8 (TRPM8), serotonin 1A receptor (5-HT1A), glycine receptors...

Besides, several studies have described CBD as a multitarget molecule, acting as an adaptogen and as a modulator, in...

Moreover, it is not completely understood whether these effects are related to CBD or to other organic compounds present in Cannabis extracts, such as...

An open-label pilot study conducted in PD patients showed that oral doses of CBD ranging from 150-400 mg/day, combined with classic...